Ectopic Pregnancy

Ectopic pregnancy post treatment - FAQs | Locally Healthy

Twitter Facebook YouTube Sign in | Register Ectopic pregnancy post treatment - FAQs Published Wed, 2011-03-02 15:28; updated 4 years ago.


Usually, we advise you wait for 3 months or 2 full menstrual cycles, whichever is the soonest. The first bleed that occurs in the first week or so of treatment for ectopic is not considered as a period - this is the bleed that occurs in response to falling hormones associated with the lost pregnancy.


This allows the cycle to return and there to be a clear LMP date, to date a new pregnancy from. It also allows the internal inflammation and bruising to heal and for the necessary process of grief to surface and be worked through.


Some studies do suggest that women who conceive immediately after treatment for ectopic pregnancy are more at risk of suffering a subsequent ectopic. Furthermore, the incidence of miscarriage (which is not in any way linked to ectopic) is generally very high, with approximately a third of first trimester pregnancies ending in miscarriage, so you really do need to feel strong enough to face whatever is coming next.


This three month wait is particularly important if you have been treated with methotrexate. This is because the methotrexate may have reduced the level of folate in your body which is needed to ensure a baby develops healthily. For example, it could result in a greater chance of the baby having a neural tube defect such as hare lip, cleft palate, or even spina bifida or other NT defects. The drug is metabolised quickly but can affect the quality of your cells, including those of your eggs and the quality of your blood for up to 3 or 4 months after it has been given. The medicine can also affect the way your liver works and so you need to give your body time to recover properly before a new pregnancy is considered. The current advice is to take folic acid for several months before you conceive. You must not begin to take folic acid supplements until the hCG levels have fallen to below 5 mIU/mL. Once your blood hCG levels have dropped, if you wish to become pregnant again, you should recommence your folic acid supplements several weeks or months before you conceive.


Our current medical advice, having reviewed this recently (2009), is that if you have had two injections you should wait until your hCG levels have fallen to below 5mIU/mL and then be taking a folic acid supplement for 12 weeks before you try to conceive. This means that you are normally giving yourself three to three and a half months or so before you try again.


This depends what you mean. It is possible to become pregnant within a very short time after being treated for an ectopic pregnancy if you have unprotected intercourse. Because it can take several weeks for your period to return, and ovulation needs to take place before the period can arrive, it is possible to become pregnant even before your period has returned. We recommend waiting for 2 proper cycles or three months, whichever is the sooner, following surgery or treatment with methotrexate to allow the body to heal and your emotions to surface and be dealt with. Having sex is itself not dangerous to you, as long as you do not find it painful. Many doctors suggest waiting until after you have had your first proper period, which means waiting until around 6 weeks, to allow full healing of the muscles and by that time you should have had your first period, giving you confidence that your body is returning to its normal rhythm.


If you are being managed expectantly, or if you have been treated with methotrexate, you will be having your hormone levels measured. As hCG levels drop, the risk of rupture diminishes. However, unfortunately, the risk remains even with very low levels in an ectopic pregnancy. For this reason we suggest you avoid sexual intercourse which involves penetration until the levels are down to less than 5 mIU/mL. Anything that increases intra-abdominal pressure is best avoided. Ultimately though, the decision about when to have sexual intercourse again is one for you and your partner and should be based on when you feel ready, which for some is earlier than 6 weeks or with levels less than 5 mIU/mL, and for others later. Of course this doesn’t mean you can’t find other ways to satisfy each other, if you feel up to that.


This depends very much on the health of your tubes. It is usually possible to conceive and over all 65% of women are healthily pregnant within 18 months of an ectopic pregnancy.


Women are advised to avoid pregnancy usually for two complete cycles or three months after experiencing an ectopic pregnancy. This waiting time is an opportunity for the body to recover from treatment and to begin to grieve for the loss of the pregnancy. However, how to prevent pregnancy can be a issue for some women. Allowing the body to recover, ovulation to occur and the first period to arrive is often suggested by doctors the ideal waiting period before women begin to have full penetrative intercourse (sex) again. Some couples, however, feel they want to have sex before this time and that is when the issue of contraception needs to be considered.


If you are still waiting for your first period but decide to have intercourse, then the suggested method of preventing pregnancy is one of the barrier methods (cap, condom, diaphragm, femidom). Introducing a synthetic hormone in the form of a contraceptive pill before this prevents the body from ovulating and establishing a normal pattern.


After the first period has arrived, either continuing with barrier methods or the combined contraceptive pill are usually the methods of choice.


This question presents a considerable dilemma and it is one that affects almost all post-ectopic women.


IUDs or coils are renowned for preventing pregnancy in the uterus but are not effective in preventing pregnancy elsewhere. The reason they are suggested as an unsuitable method in a woman who has suffered ectopic is because the ectopic has already indicated that there was damage to the tube that was affected – this suggests that the remaining tube may also be damaged.


With a coil in place, the sperm and egg can still meet in the fallopian tube – and fertilisation can and often does take place. When things then progress as they should and the egg arrives in the uterus, the coil makes it a hostile place and so conception does not continue because implantation cannot happen. The egg expires and is passed in normal menstrual blood (you can’t see it, it’s smaller than a pinprick, and is in fact not visible to the naked eye). The problem with a coil is that if you have a damaged tube(s) and the fertilised egg gets stuck, the fallopian tube will temporarily be an environment where implantation can take place (although it shouldn’t) and it can result in a subsequent tubal ectopic pregnancy.


A Mirena coil is thought to be more suitable than one of the other coils because it releases a small dose of progesterone – progesterone prevents ovulation in many instances, but not all. Unfortunately it is not foolproof and women do become pregnant with a Mirena in situ. However a Mirena coil is a progesterone only contraceptive, and these are contra-indicated for women with a history of ectopic pregnancy.


Progesterone Only Contraceptives (POCs) are associated with a higher incidence of ectopic pregnancy. The advice of our medical advisers here is as follows:


“Delaying conception is advisable because we know one of the actions of synthetic progesterone is to thicken the mucal secretions of the fallopian tubes and we have no definitive information on how long it takes for this action to be reversed and so believe it may contribute to ectopic pregnancy.”


There is no definitive research to refute or verify this hypothesis but the advice is based on the knowledge we do have about the actions of synthetic progesterone and its known link to ectopic pregnancy.


Progesterone Only Contraceptives include contraceptive implants (if used, we recommend delaying conception for several months after removal), the mini-pill or progesterone only pill, contraceptive injections (such as depo provera) and the Mirena Coil.


In control groups, women on the combined oral contraceptive were no more likely to suffer ectopic pregnancy, when they stopped taking it, than women who were not on the pill in the first place – thus suggesting that the oral combined contraceptive pill is NOT linked to ectopic pregnancy. However, there was a noted increase in the rate of women who suffered ectopic pregnancy if they became pregnant whilst taking the progesterone only contraceptive pill and it is now listed as one of the precautions in the product data. Likewise, the morning after emergency contraceptive pill is now available as a progesterone only pill and there is an increased risk of ectopic pregnancy with this form of contraception. Again this is noted in the product data.


For women with a history of ectopic pregnancy, unless the risk outweighs the potential benefits, we suggest that the barrier methods (cap, condom, diaphragm, femidom), the combined oral contraceptive or Natural Family Planning are the most suitable alternatives.


With all contraception, you and the prescribing clinician need to ask the same question – do the benefits of this to the individual outweigh the risk? Doing this means that you can decide upon the most suitable method of contraception for you as an individual and it might be that you decide on one of the methods which is usually advised against. The issue really is about what suits you and how much you need to prevent pregnancy.


Depending on which treatment you have had, a varying amount of pain or discomfort may continue for several weeks afterwards as the healing process continues and scarring continues to heal. This should lessen as time progresses. However, it is not unusual to still report some discomfort several months after an abdominal operation.


An adhesion is a band of scar tissue that binds two parts of your tissue together. They should remain separate. Adhesions may appear as thin sheets of tissue similar to plastic wrap or as thick fibrous bands.


The tissue develops when the body’s repair mechanisms respond to any tissue disturbance, such as surgery, infection, trauma, or radiation. Although adhesions can occur anywhere, the most common locations are within the stomach, the pelvis, and the heart.


Abdominal adhesions are a common complication of surgery, occurring in up to 93% of people who undergo abdominal or pelvic surgery. Abdominal adhesions also occur in 10.4% of people who have never had surgery. Most adhesions are painless and do not cause complications, but are believed to contribute to the development of chronic pelvic pain.


Adhesions typically begin to form within the first few days after surgery, but they may not produce symptoms for months or even years. As scar tissue begins to restrict motion of the small intestines, passing food through the digestive system becomes progressively more difficult.


Pelvic adhesions may involve any organ within the pelvis, such as the uterus, ovaries, fallopian tubes, or bladder, and usually occur after surgery. Pelvic inflammatory disease (PID) results from an infection (usually a sexually transmitted disease) that frequently leads to adhesions within the fallopian tubes.


It is a good idea to keep a ‘pain diary’ so that if you find the situation does not ease over a few months, you can go back to your doctor with dates, times and evidence of how it is affecting you. This can be very helpful to medical practitioners when deciding upon how to manage the symptoms.


You may get sore breasts immediately after and for some weeks after the operation as they get used to not being pregnant. They may get sore again leading up to the next period.


Bloatedness is a reaction to the operation and the inflammation following this. The length of time it continues varies, but it should settle within 6 weeks. If it continues for longer it may be a sign that you have some ongoing infection and you should see your GP.


After any abdominal operation there is some scar tissue. The abdominal scars should make no difference to your future chances. The tube that was operated on may have been removed, or at least damaged from the operation, but pregnancy is usually achieved through the other tube anyway, irrespective of whether or not the tube was salvaged. Sometimes adhesions form in the abdomen as a result of surgery and these can sometimes compromise the remaining tube, but only time will tell. Even so, overall, 65% of women are pregnant again within 18 months of an ectopic pregnancy and some studies suggest that more women (around 85%) are pregnant after 2 years.


Following an ectopic pregnancy, it is not unusual to feel pain and discomfort in the abdomen. Awareness of such feelings can be heightened as a result of the experience of losing a pregnancy. There are a number of reasons why you may be aware of the aches in your abdominal area. It could be that your normal cycle is trying to resume, the pain you are experiencing might be due to your body preparing to ovulate, or your period might be about to arrive. If after two or three months, you have continuing abdominal pain, this could be being caused by scarring, known as adhesions (scar tissue that connects two or more body structures together) and may settle over time. It could be that your awareness of your menstrual cycle and your ovulation have been heightened. Many women report that they are aware of ovulation pain after an ectopic, when they have never experienced it before. It might simply be down to heightened perception and awareness because of the experience you have been through. If the pain is persistent and is becoming worrying, we would suggest that you keep a diary. Record in your diary when your period starts, when the pain is experienced and how the pain would be scored on a scale of 0 to 10 ( 0 being no pain, 10 being pain requiring a trip to hospital ). Keep a record of what helps the pain. These might include heat (hot water bottle), exercise, rest, pain relievers (make a note of what kind). After about 8 weeks, make an appointment to go see your doctor to discuss the diary records you have been keeping.


If you are treated medically with Methotrexate or if you had your tube salvaged, you need to have your blood monitored as the risk of persistent ectopic is greater. If you had your tube removed the risk is low and blood testing is not normally necessary, although some doctors do check it once either prior to the woman leaving hospital, or after a week or so to make sure levels are dropping.


Not really. It is useful to check around 6 weeks to make sure all is well and that your periods are starting again. Many hospitals offer a follow up appointment but some do not. If you haven’t been given a follow up appointment at the hospital, your GP can do a post operative checkup for you, but as long as you feel OK, there is no real medical need to see a doctor. You may find it beneficial to talk through what happened with a medical professional, and this is the most usual reason for wanting to see a doctor at this stage. If you have been allocated a follow up appointment at hospital this usually involves the doctor reviewing your medical notes, enquiring as to your health and recovery since the operation and discharging you. Only rarely will the doctor examine your tummy or look at your scars.


You may have had several questions come to mind since your treatment and if you haven’t already done so it is a good idea to write them down – better still write them out twice and give one list of questions to the doctor and keep the other yourself and mark them off, noting the replies as the doctor answers you. Did the doctor see any obvious reason why you had suffered the ectopic pregnancy at the time of surgery? Any damage to the fallopian tube for example. Was there any evidence of scar tissue or adhesions elsewhere in your abdomen? Did your remaining tube look healthy and intact? How long would the doctor consider it reasonable for you to try to conceive without success before he or she would see you again? Will you need a separate referral for this? If and when you are next pregnant, what sort of support or early pregnancy screening will be available to you?


Normally, you can shower 24 hours after an operation on your abdomen (tummy) and take a bath after 48 hours. It is a good idea to make sure someone is around when you get into the bath, in case you find it uncomfortable or tricky to get out. Don’t rub or wash the scars – gentle washing in warm water with a mild soap or body wash gel, avoiding the actual scars, is all that is needed. If for some reason it is not advisable to take a bath, you will usually be told this as part of your discharge information. If you are in any doubt, ring the ward from which you were discharged and ask them. Dissolvable stitches often rely on the patient taking regular baths to help the stitches dissolve.


Some people take longer to recover than others. It depends on how much blood you lost and what operation you had. The bigger the operation and the more blood lost, the longer it takes to feel yourself again. Usually you should be fully recovered physically by 6 weeks, but in some people it may take longer. As long as you are making progress, you should not worry.


Methotrexate can also leave you feeling quite exhausted in the first early days of treatment and you should take things gently, at a slower pace, until your energy levels return.


This depends on how you were treated and, if you had an operation, the type of surgery you had. If you had keyhole surgery, you could start gentle exercise within 2 weeks of the operation. If you had open surgery then you should wait 6 weeks for your abdomen to heal. If you were treated with Methotrexate you should not resume exercise until your hCG levels are falling consistently and are in the low 100′s. Exercise like swimming is usually safe, as long as the wounds are healing or your hCG levels are low, as this is a non-impact sport.


Depending upon the type of surgery you had you are very likely to be advised not to drive. The length of time you are advised not to drive for will depend upon the surgery you had. You will also need to check with your insurers when they consider it safe for you to drive after the more major procedure of laparotomy because different brokers’ and underwriters’ policies vary. Driving is not prohibited after medical treatment with methotrexate or expectant management but you should feel comfortable to be able to do an emergency stop before you take control of any vehicle.


This depends on the way you were treated and what type of work you do. In some cases you could return to work with a few weeks if you had keyhole surgery and your job is not too strenuous, but you may feel tired and find it difficult to cope. Coming back part-time, if this is an option, may be a good idea. Women treated with Methotrexate sometimes work through the treatment but others find managing the loss of a baby in this way too difficult to work through. In general, after 6 weeks you should be able to return to most jobs from a physical point of view, but some women take more time off to help them deal with the psychological impact of their loss.


There is no evidence that an ectopic pregnancy affects menstrual periods or changes the timing of menopause. However, women often report an irregularity in their cycle following an ectopic pregnancy and, if it was necessary to undertake surgery on the ovary or remove one of the ovaries, this can result in menopause developing slightly earlier. However, the impact does not appear to be significant.


The advice given to mothers who are taking regular oral doses of methotrexate, not for an ectopic pregnancy but to treat another entirely different condition, is NOT to breastfeed during their treatment.


Methotrexate is excreted into breast milk in low concentrations. The significance of this is not yet known. However, because the drug may accumulate in neonatal tissues, breast feeding is not recommended in long-term use of methotrexate. The American Academy of Paediatrics considers methotrexate to be contraindicated during breast feeding because of several potential problems, including immune suppression, neutropenia, adverse effects on growth, and carcinogenesis.


HOWEVER, the advice for women who have had Methotrexate for the treatment of ectopic pregnancy is different. In this case, Methotrexate is usually given as a one off dose (or occasionally two doses) by injection into a large muscle. It antagonises folic acid (vitamin B9) and causes it to be excreted, depleting the body of this essential vitamin.


If your baby is less than a year old and if breast milk is the sole source of nutrition, we advise avoiding breast feeding for at least four weeks following treatment with Methotrexate. If your child has been weaned, and is taking a balanced diet of mixed foods with an occasional breast feed for comfort, you may choose to start feeding again sooner than this.


In ectopic pregnancy, when one dose of methotrexate has been given, the risk is not the accumulation in neonatal tissues. The risk is that the milk will be of poor quality and of little nutritional use, due to the missing essential vitamins on which the body depends to support the division of rapidly dividing cells. This is very significant in small children as they are growing and relying on this crucial process.


The bleeding you have after surgery, treatment with Methotrexate or if you are managed “expectantly”, is not actually classed as a period. This is your body expelling the thickened lining of the uterus. Once the beta hCG levels have dropped, the chemical signals to retain the thickened uterine lining that has built up in preparation for pregnancy, are no longer being produced and so the lining of the uterus is shed. The process involves vaginal bleeding and the material may be clotty, heavy, dark in appearance or appear just like one of your normal period bleeds. The bleeding can continue for up to six weeks and it is not unusual to bleed, stop, and have spotting during this time.


The body is a very clever thing and before you can have a period you have to ovulate. It is perfectly possible to ovulate within 14 days after surgical treatment and almost as soon with Methotrexate treatment, so it is important to be aware that it is possible to become pregnant without having a proper period first, if you are not using some form of contraception.


You are usually advised to wait for at least two normal cycles or three months before trying to conceive again, as this allows your body to recover from treatment and to prepare for pregnancy next time. If you have been treated with Methotrexate it is especially important to wait (please see the top of this page for details on the reasons we advise this).


You will continue to have periods, which are likely to arrive around once every month. The fallopian tubes play no part in controlling your period cycle. The cycle is controlled by hormones produced in different sites in the body but predominantly in the ovaries.


No. Usually your periods will settle in to a regular cycle, even though one of the ovaries has been removed. Often the other ovary compensates and produces sufficient hormones to control the cycle.


Your periods can take a while to re-establish and they can re-start anything between 2 and 10 weeks after surgery, or once hCG levels have fallen below about 100mIU/mL. Most women find that their period arrives sometime around week 6 or 7 after surgery, and at some time in the 4 weeks after their hCG levels have fallen to 0 if treated with Methotrexate.


The first period may be more painful or less so than usual, heavier or lighter, last for longer or shorter than usual – there really is no set pattern. You should be able to manage the discomfort with over-the-counter pain relief and should not be soaking a pad in less than an hour. If this is not the case, you should seek medical attention. Your periods may be a little irregular or erratic but broadly speaking, doctors consider periods of between 23 to 42 days to be within normal parameters. If the first day of your last period was more than 42 days ago, make an appointment with your doctor to discuss the possible reasons for this.


Following surgery, we usually advise you wait for 2 of these cycles before trying to conceive again, to allow your body to heal and your emotions to surface and be dealt with. In the case of treatment with Methotrexate, we advise you to wait for at least 3 months after the last injection and if you had two injections some doctors suggest 6 months.


You will continue to have normal periods every month. A period is the shedding of the lining of the womb. The presence of the tubes makes no difference to this. Periods continue even if both tubes have been removed. In fact, periods usually continue normally even in the very rare cases when one of the ovaries is removed as part of the surgical process.


Will my periods return to the normal after my ectopic – before they were 25/26 days – this time I’m 30 days (I’ve checked I’m not pregnant) is this all right?


The first period can occur up to 6 weeks after the ectopic pregnancy although it may not be like your normal period. It might be heavier or lighter and it may be more painful than normal. The period after that is usually more like your normal pattern. However, although there is no medical reason for it, women do often report some irregularity to their cycle for several months after an ectopic pregnancy.


After surgery for an ectopic pregnancy you may have some adhesions which might cause some pelvic pain and pain at ovulation but this usually settles.


Counselling can be extremely effective at the right time but it is not a quick fix and it won’t take away the pain of first grief. That experience of grief, scary as it may be, is healing and forms part of your own recovery from one of the most significant events likely to have happened in your life. We urge women who have experienced the loss of an ectopic pregnancy to please be gentle with yourself and allow yourself the time you need to grieve. For more information about grief and counselling please follow this link.


In all cases, a woman who has suffered an ectopic pregnancy should contact her GP as soon as she knows she is pregnant. Usually you will be referred to an Early Pregnancy Unit. Here it is normal to arrange an ultrasound scan at around 6 weeks to check the pregnancy is in the womb. If your period is late, if menstrual bleeding is different from normal or if there is abnormal abdominal pain, you should ask to be examined and remind the doctor if necessary that you have had a previous ectopic pregnancy.


If you wish to view your health records, it may not be necessary for you to make a formal application to do so. Nothing in the law prevents health professionals from informally showing you your own records. You could make an informal request during a consultation, or by ringing the surgery or hospital and arranging a time to visit and see your records.


However, if you wish to make a formal request to see your health records under the Data Protection Act, you should apply in writing to the holder(s) of the records. If you wish to see your GP records, you should write directly to your GP or to the practice manager. If you wish to see your hospital records, you should write to your hospital Patients Services Manager or Medical Records officer.


You may be charged a fee. The maximum fee (March 2010) that can be charged to provide access and a copy of your records is: records held totally on computer: up to a maximum £10 charge, records held in part on computer and in part manually: up to a maximum £50 charge, and records held totally manually: up to a maximum £50 charge.


The maximum fee that can be charged to provide access to your records (where no copy is required) is: records held totally on computer: up to a maximum £10 charge, unless the records have been added to in the last 40 days, when no charge can be made, records held in part on computer and in part manually: up to a maximum £10 charge, unless the records have been added to in the last 40 days, when no charge can be made, and records held totally manually: up to a maximum £10 charge, unless the records have been added to in the last 40 days, when no charge can be made.


You are entitled by law to receive a response no later than 40 days after your application is received and any relevant fee has been paid. You will then be given an appointment to see your records.


If you have requested a copy of your records, it should be written out in a form that is understandable to you – this means that abbreviations or complicated medical terms should be explained. If you still don’t understand any part of the record, the health professional holding the record should explain it to you.


For more information on accessing files, please look at this patient information leaflet. Please also see this BBC article on electronic medical records. Recommended links:


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