Ectopic Pregnancy

BBC News - Protein level could aid ectopic pregnancy test - study

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At present, finding out if a foetus is developing outside of the womb as occurs in these pregnancies requires ultrasounds and several blood tests.


But Edinburgh University scientists say the protein activin B could be key to early diagnosis and treatment.


Ectopic pregnancies put the mother at risk because of the possibility that the area where it is growing - usually the fallopian tube but sometimes the cervix or ovaries - can rupture, causing potentially fatal internal bleeding.


In the UK, five women a year die of this - in the developing world, one in 10 of these pregnancies ends in the death of the mother.


So to protect women's health, these pregnancies are usually terminated once the diagnosis is confirmed.


Investigating whether a pregnancy is ectopic costs the NHS around 9m per year, and also places immense strain on the mother.


But Edinburgh researchers writing in the journal Human Reproduction say they have established that women with these pregnancies have a much lower level of the protein known as activin B. They hope now to develop a simple diagnostic test.


Early diagnosis of ectopic pregnancy is a key factor in improving treatment of the condition and helping to assure a woman's future fertility Helen WilkinsonThe Ectopic Pregnancy Trust


Dr Andrew Horne, of the University of Edinburgh's Centre for Reproductive Biology, said: Diagnosing an ectopic pregnancy is incredibly complex yet detecting the condition early on can ease the emotional trauma of those affected.


Early diagnosis can also prevent future fertility problems and improve the effectiveness of treatment as well as save the NHS millions of pounds. Understanding how proteins are expressed is pivotal in developing a simple blood test that could be used to detect an ectopic pregnancy.


Studies that give us the tools to establish earlier diagnosis and improve the outcomes of treatment are essential to improve upon what is currently available, said the charity's director Helen Wilkinson.


Early diagnosis of ectopic pregnancy is a key factor in improving treatment of the condition and helping to assure a woman's future fertility, therefore we welcome any advancement that could be made in this area including the University of Edinburgh's planned research into the possibility of a simple diagnostic test. Bookmark with: Delicious Digg reddit Facebook StumbleUpon What are these? E-mail this to a friend Printable version


Print Sponsor SEE ALSO Ectopic pregnancy 08 Feb 03 | Medical notes Policy change after ectopic error 09 Aug 06 | Manchester Surgeons praised after ectopic op 08 Aug 06 | Essex 'Miracle baby' born after surgery 12 Apr 06 | Southern Counties RELATED INTERNET LINKS Ectopic Pregnancy Trust The BBC is not responsible for the content of external internet sites TOP HEALTH STORIES Stem cell method put to the test Hospitals 'eyeing private market' Low vitamin D 'Parkinson's link' MOST POPULAR STORIES NOW SHARED READ WATCHED/LISTENED Most popular now, in detail SHARED READ WATCHED/LISTENED BBC News BBC News BBC News BBC News BBC News BBC News BBC News BBC News BBC News BBC News Most popular now, in detail SHARED READ WATCHED/LISTENED Unnamed page Unnamed page One-minute World News Unnamed page Chinese star's acts of generosity faked The perks of being US President BBC News BBC News Unnamed page BBC News Most popular now, in detail FEATURES, VIEWS, ANALYSIS Ghost town Has China's housing bubble burst? The guerilla plant How the world's oldest clove tree defied an empire Walking away Why Royal Ballet principal Sergei Polunin quit Skip to top PRODUCTS SERVICES E-mail news Mobiles Widgets Alerts News feeds Podcasts BBC iDSign in Search term: BBC navigation News Sport Weather Capital TV Radio More CBBC CBeebies Make It Digital Food iWonder Bitesize Music Earth Arts Taster Local Northern Ireland Scotland Wales


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